Limitations of Noninvasive Tests-Based Population-Level Risk Stratification Strategy for Nonalcoholic Fatty Liver Disease
Digestive Diseases and Sciences(2024)
摘要
Background Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are highly prevalent but underdiagnosed. Aims We used an electronic health record data network to test a population-level risk stratification strategy using noninvasive tests (NITs) of liver fibrosis. Methods Data were obtained from PCORnet ® sites in the East, Midwest, Southwest, and Southeast United States from patients aged ≥ 18 with or without ICD-10-CM diagnosis codes for NAFLD, NASH, and NASH-cirrhosis between 9/1/2017 and 8/31/2020. Average and standard deviations (SD) for Fibrosis-4 index (FIB-4), NAFLD fibrosis score (NFS), and Hepatic Steatosis Index (HSI) were estimated by site for each patient cohort. Sample-wide estimates were calculated as weighted averages across study sites. Results Of 11,875,959 patients, 0.8
更多查看译文
关键词
Nonalcoholic steatohepatitis,Fibrosis-4 index,NAFLD fibrosis score,Hepatic Steatosis Index,NAFLD screening,Metabolic dysfunction-associated steatotic liver disease
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要