Acquisition of Extended-Spectrum β-Lactamase GES-6 Leading to Resistance to Ceftolozane-Tazobactam Combination in Pseudomonas aeruginosa

Laurent Poirel,José-Manuel Ortiz De La Rosa,Nicolas Kieffer,Véronique Dubois,Aurélie Jayol,Patrice Nordmann

Antimicrobial Agents and Chemotherapy（2019）

引用 17|浏览0

暂无评分

摘要

A clinical Pseudomonas aeruginosa isolate resistant to all β-lactams, including ceftolozane-tazobactam and carbapenems, was recovered. It belonged to sequence type 235 and produced the extended-spectrum β-lactamase (ESBL) GES-6 differing from GES-1 by two amino acid substitutions (E104K and G170S).

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要