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Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T FH cells

Jennifer M. Dan,Colin Havenar-Daughton,Kayla Kendric,Rita Al-kolla,Kirti Kaushik,Sandy L. Rosales, Ericka L. Anderson,Christopher N. LaRock,Pandurangan Vijayanand,Grégory Seumois,David Layfield,Ramsey I. Cutress,Christian H. Ottensmeier,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Victor Nizet,Marcella Bothwell,Matthew Brigger,Shane Crotty

Science Translational Medicine（2019）

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摘要
Recurrent tonsillitis is a multifactorial disease associated with an aberrant tonsillar germinal center response to group A Streptococcus .
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