A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome
Sabrina Bondu,Anne-Sophie Alary,Carine Lefèvre,Alexandre Houy,Grace Jung,Thibaud Lefebvre,David Rombaut,Ismael Boussaid, Abderrahmane Bousta,François Guillonneau,Prunelle Perrier,Samar Alsafadi,Michel Wassef,Raphaël Margueron,Alice Rousseau,Nathalie Droin,Nicolas Cagnard,Sophie Kaltenbach,Susann Winter,Anne-Sophie Kubasch,Didier Bouscary,Valeria Santini,Andrea Toma,Mathilde Hunault,Aspasia Stamatoullas,Emmanuel Gyan,Thomas Cluzeau,Uwe Platzbecker,Lionel Adès,Hervé Puy,Marc-Henri Stern,Zoubida Karim,Patrick Mayeux,Elizabeta Nemeth,Sophie Park,Tomas Ganz,Léon Kautz,Olivier Kosmider,Michaëla Fontenay Science Translational Medicine（2019）
摘要
A variant erythroferrone contributes to hepcidin modulation and systemic iron accumulation in patients with SF3B1 -mutated myelodysplastic syndrome.
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