Prevention of Hypotension After Spinal Anaesthesia for Cesarean Section: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials

( Anaesthesia . 2020;75:109–121) The potential for maternal hypotension is one key risk of spinal anesthesia for elective cesarean delivery (CD). A variety of methods to prevent postspinal hypotension during CD are recommended in the literature. While an international consensus statement published in 2018 recommended prophylactic vasopressors for all CDs it did not take into account the risks associated with these agents. Also, a recent meta-analysis comparing different methods to prevent hypotension was inadequate to determine treatment efficacy. The aim of this study was to determine the relative efficacy of interventions, including vasopressors, to prevent hypotension associated with spinal anesthesia during elective CD.