Antiviral Activity of Porcine IFN-λ3 and IFN-α against Porcine Rotavirus In Vitro.

Lishuang Deng,Yue Yin,Zhiwen Xu,Fengqin Li,Jun Zhao,Huidan Deng,Zhijie Jian,Siyuan Lai,Xiangang Sun, Ling Zhu

Molecules（2022）

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摘要

Interferons (IFNs) play a major role in the host's antiviral innate immunity. In response to viral infection, IFNs bind their receptors and initiate a signaling cascade, leading to the accurate transcriptional regulation of hundreds of IFN-stimulated genes (ISGs). Porcine rotavirus (PoRV) belongs to genus RotavirusReoviridae

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antiviral activity,IFN-λ3,IFN-α,PoRV

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