Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs

Chris H. Wendt,Brian J Sandri,Laia Masvidal,Carl Murie,Margarita Bartish,Svetlana Avdulov,LeeAnn Higgins,Todd W. Markowski,Mark S. Peterson,Jonas Bergh,Ping Yang,Charlotte Rolny,Andrew H. Limper,Timothy J. Griffin,Peter B. Bitterman,Ola Larsson

Annals of the American Thoracic Society（2018）

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摘要

Rationale: Chronic obstructive pulmonary disease (COPD) is an independent risk factor for lung cancer, but the underlying molecular mechanisms are unknown. We hypothesized that stromal cells compri...

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关键词

chronic obstructive pulmonary disease,gene,phenotype,cancer-promoting

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