Spontaneous Mutational Frequency and FKS Mutation Rates Vary by Echinocandin Agent against Candida glabrata

Ryan K. Shields,Ellen G Kline,Kelley R. Healey,Milena Kordalewska,David S. Perlin,M. Hong Nguyen,Cornelius J. Clancy

Antimicrobial Agents and Chemotherapy（2019）

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摘要

Echinocandins are front-line agents for treatment of invasive candidiasis. There are no reported agent-specific differences in Candida mutational frequency of resistance or propensity to develop FKS mutations.

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关键词

mutational rates vary,spontaneous mutational frequency,echinocandin agent

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