Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients
Blood(2013)
摘要
Key Points Only a complete disruption of TP53 function increases the risk for disease progression in previously treated CLL patients. MiR-34a expression significantly correlates with the predicted TP53 activity in previously treated CLL patients with TP53 abnormalities.
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关键词
leukemia,tp53,disease progression
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