Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Blood（2018）

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摘要

Key Points Identification of genes frequently mutated in cHL, fostering tumor growth in a manner amenable to pharmacological targeting. Mutated genes include the almost ubiquitous targeting of JAK-STAT pathway members, as well as GNA13, XPO1, and ITPKB.

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关键词

lymphoma,hodgkin,pervasive mutations,jak-stat

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