Association Between Serum 3-Hydroxyisobutyric Acid and Prognosis in Patients With Chronic Heart Failure ― An Analysis of the KUNIUMI Registry Chronic Cohort ―

Wataru Fujimoto,Manabu Nagao,Makoto Nishimori,Masakazu Shinohara,Makoto Takemoto,Koji Kuroda,Soichiro Yamashita,Junichi Imanishi, Masanori Iwasaki,Takafumi Todoroki, Mitsuru Okuda,Hidekazu Tanaka,Tatsuro Ishida,Ryuji Toh,Ken‐ichi Hirata

Circulation journal（2023）

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摘要

Background: Diabetes increases the risk of heart failure (HF). 3-Hydroxyisobutyric acid (3-HIB) is a muscle-derived metabolite reflecting systemic insulin resistance. In this study, we investigated the prognostic impact of 3-HIB in patients with chronic HF.

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关键词

chronic heart failure,heart failure,kuniumi registry chronic cohort,prognosis

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