Singapore Lung Cancer Screening through Integrating CT with Other Biomarkers (SOLSTICE), A Single Arm Lung Cancer Screening Study

Lung cancer is one of the leading causes of cancer-related mortality in Singapore and globally, with majority of patients diagnosed in the advanced stage where the disease is incurable. Intervention by screening to detect pre or early-stage cancer may potentially provide the best tool to improve mortality and morbidity. The cornerstone of lung cancer screening studies thus far has been low-dose computed tomography (LDCT), with majority of recommendations for implementation in high risk individuals defined by smoking status and age.