An ultra-sensitive fluorescent probe for recognition of aluminum ions and its application in environment, food, and bio-imaging

The concentration of Aluminum ions (Al3+) is closely related to the ecological environment, food safety, and human health, with excessive accumulation of Al3+ causing irreversible damage to both the ecological balance and human health. Therefore, a fluorescent probe ABHS, based on aminobenzoylhydrazide Schiff-base, was designed and synthesized in one step with a high yield. ABHS can form a 1:1 coordination complex with Al3+ in a pure water system. It exhibits ultra-sensitive and accurate detection of Al3+ even at low concentration of Al3+, with the detection limit of 6.7 nM. Furthermore, ABHS demonstrated significant enhancement of specific fluorescence for Al3+, with rapid response times, good stability, and robust resistance to interference. Importantly, ABHS has shown excellent detection and imaging capabilities even in complex real environmental samples, food samples, and living organisms.