Nvasive versus non invasive positive pressure ventilation in acute lung injury and acute respiratory distress syndrome: a comparative cohort study

Background: Noninvasive positive pressure ventilation (NPPV) for acute respiratory failure in the intensive care unit (ICU) is associated with a marked reduction in intubation rate, complications, hospital length of stay and mortality. Multiple studies have indicated that patients failing NPPV have worse outcomes compared with patients with successful NPPV treatment; however limited data is available on risks associated with NPPV failure resulting in (delayed) intubation and outcomes compared with initial intubation. Aim of our study to determine mortality rate and length of hospital stay for ARDS AND ALI patients who received NIPPV and its comparison with ARDS patients on IMV and to determine the predicting factors for NIPPV failure and IMV use. This study was an analytical study. This was Method and study design: a comparative cohort study in which 68 patients were included prospectively. Patients with age >6 Results: 0 years had poor outcomes as they needed IMV & NIPPV followed by IMV more than patients with age <60 years. Patients on IMV & NIPPV followed by IMV had a high mortality rate as compared to patients on NIPPV. Our study stat Conclusions: es that patients who were on NIPPV & got success they were having good outcomes in terms of mortality & those who failed NIPPV & required IMV got poorer outcomes.