Acid‐catalyzed One Pot Synthesis of Thiazolo[4,5‐b]indolamines from α‐Diazoimidamides and Thioureas

Abstract A novel synthetic method for the formation of thiazolo[4,5‐ b ]indol‐2‐amines from α‐diazoimidamides and mono ‐substituted thioureas in the presence of a catalytic amount of boron trifluoride etherate and camphorsulfonic acid under mild conditions was demonstrated. This methodology has a wide‐ranging scope of α‐diazoimidamides and mono ‐substituted thioureas, amenable for upscaling experiments and further transformation.