Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies

In this Opinion article, the authors forgot to disclose their funding sources. The authors would like to acknowledge that I.V. is supported bySAF2016-76758-Rgrant from theSpanish Ministerio de Economía y Competitividad(MINECO) and byERC2014-StG637904grant from theEuropean Research Council. The authors apologize for this omission. Tumor Functional Heterogeneity Unraveled by scRNA-seq TechnologiesGonzález-Silva et al.Trends in CancerJanuary 3, 2020In BriefEffective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progression. New applications and advances occurring at a fast pace predict an imminent broad application of these technologies in many research areas. As occurred with next-generation sequencing (NGS) technologies, once applied to clinical samples across tumor types, single-cell sequencing technologies could trigger an exponential increase in knowledge of the molecular pathways involved in cancer progression and contribute to the improvement of cancer treatment. Full-Text PDF Open Access