Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

Developmental Cell(2020)

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摘要
(Developmental Cell 50, 627–643.e1–e5; September 9, 2019) As a result of author oversight in the originally published version of this article, Fiorella Cugliandolo was not included in the author list. Her name has now been included, in a position agreed by her and the other authors, and the corrected affiliations and author list appear below. This has also been corrected online. Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum PlatformZachari et al.Developmental CellJuly 25, 2019In BriefZachari et al. use genetic and imaging experiments to define the ordered steps of mitophagy induction in response to the drug ivermectin. Their findings suggest that damaged mitochondria are ubiquitinated and dynamically encased in ER strands that then provide the platform for the formation of mitophagosomes. Full-Text PDF Open Access
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关键词
selective autophagy,ubiquitin-endoplasmic-reticulum ubiquitin-endoplasmic-reticulum,mitochondria
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