Abstract 11342: Contemporary in-hospital Outcomes of Chronic Total Occlusion Interventions: Update from the Progress-cto (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) International Registry

Introduction: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is an evolving field. Methods: We examined the clinical and angiographic characteristics and procedural outcomes of 8,666 CTO PCIs performed at 36 centers between 2012 and 2021. Results: Mean age was 64±10 years and 82% of the patients were men. The prevalence of prior PCI (62%) and diabetes mellitus (43%) was high. Median ejection fraction was 54% (42%, 60%). Radial access was used in 50%. The most common target vessel was the right coronary artery (52%), followed by the left anterior descending artery (26%). The target CTOs were highly complex with mean J-CTO score of 2.4 ±1.3 and PROGRESS score of (1.3 ±1). Technical and procedural success rates were high (86% and 85% respectively) with a relatively low percentage of in-hospital major adverse cardiac events (Figure 1). The final successful crossing strategy was antegrade wire escalation in 62%, retrograde in 22%, and antegrade dissection re-entry in 16%. Median contrast volume, air kerma radiation dose and procedure time were 220 (155, 300) ml, 2.2 (1.2, 3.8) Gray and 116 (75, 172) minutes, respectively. Conclusions: High success and acceptable complication rates can currently be achieved in CTO PCI among high-volume, experienced centers.