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Leukemia-intrinsic Determinants of CAR-T Response Revealed by Iterative in Vivo Genome-Wide CRISPR Screening

Azucena Ramos,Catherine E. Koch, Yunpeng Liu-Lupo,Riley D. Hellinger,Taeyoon Kyung,Keene L. Abbott,Julia Fröse,Daniel Goulet,Khloe S. Gordon, Keith P. Eidell,Paul Leclerc,Charles A. Whittaker,Rebecca C. Larson,Audrey J. Muscato,Kathleen B. Yates,Juan Dubrot,John G. Doench,Aviv Regev,Matthew G. Vander Heiden,Marcela V. Maus,Robert T. Manguso,Michael E. Birnbaum,Michael T. Hemann

Nature Communications（2023）

Cited 2|Views7
Key words
CAR T Cells,Tumor Regression,Cancer Immunotherapy
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