Evaluation of the insulin levels increasing effect of trigona honey in mice diabetes mellitus

Objective: Many herbal medicines can be used for the therapy of several diseases, infection diseases, and metabolic diseases. Honey is naturally sweet, bee product. It is the main components are glucose, fructose, protein, amino acids, vitamins, enzymes, main carbohydrates, minerals, and bioactive components such as flavonoid, phenol, tannin, triterpenoid. Trigona honey contains vitamins that function as antibiotics, antitoxins, and antioxidants and increase the immune system. To analyze the effects of trigona honey (Tetragonula sp) on plasma insulin levels in diabetes mellitus mice. Method: True experimental pre and post to investigate the effectiveness of trigona honey. Result:Showed, P < 0.05, there were differences in the effect of trigona honey (Tetragonula sp) on plasma insulin levels. Conclusion: Daily consumption of trigona honey has a remarkable potential to increase plasma insulin, thus it can contribute to the prevention of diabetes mellitus development.