Association of the hemochromatosis (HFE) gene with pazopanib-induced transaminase elevations in renal cell carcinoma.

Chen Xu,Brian H. Reck,Vicki Goodman, Zhanxiong Xue, Lifang Huang,Colin F. Spraggs,Vincent Mooser, Leonard Cardon,Lini Pandite

Journal of Clinical Oncology（2010）

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摘要

3019 Background: Pazopanib (Votrient) has demonstrated clinical activity against multiple tumour types and is generally well tolerated. However, isolated elevations in transaminases have been obser...

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renal cell carcinoma,hemochromatosis,transaminase elevations,pazopanib-induced

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