Urinary loss of thyroid hormones: An issue to remember
ENDOCRINOLOGIA DIABETES Y NUTRICION(2023)
摘要
A 45-year-old woman suffering from primary hypothyroidism, previously well substituted with levothyroxine, was urgently referred from Primary Care to Endocrinology due to very elevated thyrotropin, free thyroxine at low limit of normality, very high cholesterol and generalised oedema. Hypothyroidism was suspected as the main aetiology of this clinical condition. A detailed examination showed nephrotic range proteinuria and the patient was finally diagnosed with lupus nephritis. Urinary loss of thyroid hormones, fundamentally linked to their transport proteins, in patients affected by nephrotic syndrome is sometimes a forgotten phenomenon and one which should be considered in patients with increased levothyroxine requirements. In this report, we present the details of this case and a brief review of the literature on this topic. (c) 2023 SEEN y SED. Published by Elsevier Espana, S.L.U. All rights reserved.
更多查看译文
关键词
Hypothyroidism,Proteinuria,Nephrotic syndrome,Thyroxin-binding globulin (TBG)
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要