l-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction

MENDELEEV COMMUNICATIONS(2023)

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摘要
We synthesized a biocompatible substrate of the peroxy-oxalate chemiluminescent reaction on the basis ofN-benzoyl-l-tyrosine ethyl ester. Its ability to interact with hydrogen peroxide was evaluated by light emission in the presence of a perylene activator. Its cytotoxicity is three times less than that of bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate (CPPO).
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关键词
peroxyoxalate chemiluminescent reaction,poly-L-lactide-PEG amphiphilic copolymers,L-tyrosine,bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate,chemo-induced PDT,micelles
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