Omicron Infections in Vaccinated Pediatric Solid Organ Transplant Recipients

John McAteer, Divya D. Kalluri,Rivka R. Abedon,Caroline X. Qin,Scott R. Auerbach,Olga Charnaya,Lara A. Danziger-Isakov,Noelle H. Ebel,Amy G. Feldman,Evelyn K. Hsu,Saeed Mohammad,Emily R. Perito,Ashley M. Thomas,Teresa P. Y. Chiang,Jacqueline M. Garonzik-Wang,Dorry L. Segev,William A. Werbel,Douglas B. Mogul

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY（2024）

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摘要

SARS-CoV-2 infection during the Omicron period was frequent amongst a cohort of vaccinated pediatric solid organ transplant recipients (pSOTRs) despite robust anti-receptor-binding domain (anti-RBD) antibody response, suggesting poor neutralizing capacity against Omicron subvariants. Breakthrough infections among pSOTRs were overall limited in severity.

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breakthrough,COVID-19,mRNA vaccination,Omicron variant,pediatrics,solid organ transplant

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