Widespread xanthomas regression by personalized lipid lowering therapy in heterozygous familial hypercholesterolemia

Francesco Sbrana,Beatrice Dal Pino, Federico Bigazzi,Tiziana Sampietro

CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS(2024)

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摘要
"The lower, the better" is the recommended approach in the management of high LDL cholesterol. Unfortunately, this does not always achieve as in the case of a 69-year-old woman referred to our Institute for her lipid profile (LDL cholesterol 412 mg/dl), bilateral xanthelasma and cutaneous xanthomas. With a maximized and personalized lipid-lowering therapies (rosuvastatin, ezetimibe, PCSK9i and lipoprotein apheresis), after only six months, the patient showed an impressive regression in her cutaneous xanthomas. (R) 2023 Sociedad Espan similar to ola de Arteriosclerosis. Published by Elsevier Espan similar to a, S.L.U. All rights reserved.
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关键词
Cutaneous xanthomas,Heterozygous familial hypercholes- terolemia,Lipid lowering therapy,Tendon xanthomas,Xanthelasma
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