Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion.

Sapir Cohen Shvefel, Joy A Pai,Yingying Cao,Lipika R Pal,Ronen Levy,Winnie Yao,Kuoyuan Cheng, Marie Zemanek,Osnat Bartok, Chen Weller,Yajie Yin,Peter P Du, Elizabeta Yakubovich,Irit Orr,Shifra Ben-Dor,Roni Oren,Liat Fellus-Alyagor,Ofra Golani,Inna Goliand, Dean Ranmar, Ilya Savchenko, Nadav Ketrarou,Alejandro A Schäffer, Eytan Ruppin,Ansuman T Satpathy,Yardena Samuels

bioRxiv : the preprint server for biology（2023）

引用 0|浏览8

暂无评分

摘要

Here, we uncover the association of expression with tumor growth and aggressiveness, specifically in low ITH tumors. These findings could facilitate the development of new strategies to treat patients with homogeneous, high- expressing tumors that are unresponsive to immune checkpoint therapy.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要