Phase-based Causality Analysis of EEG in Treatment of Major Depressive Disorder

This study analyzes causal connections between cross-hemispheric brain regions in individuals diagnosed with major depressive disorder (MDD) through Electroencephalography (EEG) data. A phase-based causality analysis technique is first validated on coupled Rössler systems and then employed on EEG recordings from MDD patients. Our results provide significant insights regarding causal influences in cross-hemispheric brain connectivity of MDD patients who exhibit an early response to medication after commencing treatment.