0D-carbon-quantum-dots/2D-MoS 2 mixed-dimensional heterojunction transistor for emulating pulsatile photoelectric therapy of visual amnesic behaviors

Amnesia is a common clinical disorder manifested by the loss of recent memory as well as global impairment in the ability to acquire new memories, which seriously affects normal life activities of humans. At present, although herbal intervention, protein synthesis inhibition, and hormone replacement can prevent or reverse amnesia, these treatments are relatively expensive and inefficient. Here, an advanced photoelectric-synergistically pulsatile therapy is used to emulate the treatment of visual amnesic behaviors using a zero-dimensional (0D)-carbon-quantum-dots/2D-MoS 2 mixed-dimensional heterojunction transistor. The photoelectric pulse could induce enough electrons to fill the trap states and accumulate at the mixed-dimensional interface. The significant biological behaviors, such as reconfigurable memorizing/forgetting behaviors and adjustable visual memory consolidation, are successfully realized in the device. More importantly, the photoelectric-synergistically pulsatile therapy for the effective treatment of visual amnesia is experimentally demonstrated for the first time. These results may provide promising opportunities for the development of medical memory diagnosis systems and human-machine realtime interactions, etc.