GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders

Lorenzo Leggio,Christian S. Hendershot,Mehdi Farokhnia,Anders Fink-Jensen,Mette Kruse Klausen,Joseph P. Schacht, W. Kyle Simmons

NATURE MEDICINE（2023）

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摘要

Preclinical and initial human studies suggest that glucagon-like peptide-1 receptor agonists may be promising treatments for alcohol use disorder, but existing approved treatments should be used until safety and efficacy is demonstrated in clinical trials.

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