Validation of dried blood spot for serological diagnosis of Hepatitis B and C: a multicentric study

Arati Mane, Reshu Agarwal, Meenu Bajpai,Suvarna Sane,Pallavi Vidhate,Partha Rakshit,Preeti Madan,Hema Gogia,Priya Abraham,Sandhya Kabra,Ekta Gupta

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE（2024）

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摘要

The present study aimed to determine diagnostic performance of dried blood spot (DBS) for the detection of Hepatitis B surface antigen (HBsAg) and Hepatitis C virus antibodies (anti-HCV) using CLIA at 3 different laboratories across India. DBS can serve as a simple and convenient alternative to plasma/serum for HBsAg detection. However for anti-HCV, site-specific validation of the assay is warranted.

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关键词

Dried blood spot,Finger-prick,Hepatitis B,Hepatitis C,Chemiluminescence

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