Frequency demodulation with magnetoelectric coreshells: A novel approach to enhanced bio-stimulation
NANOCOM '23: Proceedings of the 10th ACM International Conference on Nanoscale Computing and Communication(2023)
摘要
Magnetoelectric (ME) coreshell devices have interesting applications in biomedical technologies including biosensing, and communication, due to their strong inter--coupling between the magnetostrictive core and the piezoelectric shell. This property could be utilized for specific applications in localized bio--stimulation of cells. This paper provides a conceptual proof of using the non--linear property of ME coreshell devices for frequency demodulation and stimulation. We use the Multiphysics simulation approach, wherein the ME coreshell was biased with a DC magnetic field and perturbed through dual coil alternating magnetic fields. The combined effect of the ME non--linear magnetostriction and the dual coil perturbation resulted in the demodulation of the interference frequency component, that induced equivalent 'electrical hotspots' on the piezoelectric shell. We provide a cross model verification, where the generated electrical current density on the piezo shell was provided as an input to a Hodgkin--Huxley (HH) neural cell model to actively induce membrane potentials on the cell. Future applications as a standalone, battery- and electronics-free, controllable, multi--functional and localized coreshells for targeted drug delivery, backscatter communication and bio--stimulation, is envisioned.
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