Extracellular vesicle treatment partially reverts epigenetic alterations in chronically ischemic porcine myocardium.

Vessel plus(2023)

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摘要
Alterations in DNA methylation were identified in pig myocardium after ischemic insult, change in diet, and treatment with EVs. Hundreds of differentially methylated loci were detected, but the magnitude of the effects was low. These changes represent significant alterations in DNA methylation and merit further investigation.
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