An Isoniazid Based Schiff Base Sensor for Selective Detection of Pd 2+ Ions.

Here, we developed a novel isoniazid based fluorescent probe (E)-N'-(thiophen-2-ylmethylene)isonicotinohydrazide (TINH) through simple condensation reaction and employed for selective detection of Pd ions with a low detection limit of 4.102 × 10 M. Among the many existing cations, TINH bound Pd ions with an association affinity of 9.794 × 10 M. Adding Pd ions to ligand solution increased the absorption intensity in UV-Visible and quenched the emission intensity in fluorescence spectroscopic experiments. More importantly, this TINH complexed to Pd ions in 1:1 stoichiometric ratio. To evaluate the stability of complexed system, pH experiments has been performed. The binding insights among the ligand and Pd ions has been confirmed by IR spectroscopic and MASS spectrometric methods. Additionally, TINH also applied to real water samples for the identification and measurement of Pd ions. Hence, this system could be highly applicable for detection of Pd ions in environmental and industrial samples with in low detection range.