Nickel-Catalyzed Three-Component Alkylarylation of Alkenyl N-Heteroarenes
Organic letters(2023)
摘要
A nickel-catalyzed three-component alkylarylation of alkenyl N-heteroarenes with alpha-bromocarboxylates and aryl boronic acids is reported. The protocol provides a new method to access a variety of N-heteroarene substituted diarylalkanes in moderate to good yields. It features mild reaction conditions, cheap nickel catalyst, readily available substrates, and broad substrate scope.
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