Intramuscular Administration of Tranexamic Acid in a Large Swine Model of Hemorrhage with Hyperfibrinolysis.

Christopher J Haberkorn, Carter C Severance,Nathan C Wetmore,Walker G West,Patrick C Ng,Francesca Cendali,Christopher Pitotti,Steven G Schauer,Joseph K Maddry,Vikhyat S Bebarta,Tara B Hendry-Hofer

The journal of trauma and acute care surgery（2023）

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摘要

In the large swine model of hemorrhage with hyperfibrinolysis, IM TXA is bioequivalent and equally efficacious in preventing hyperfibrinolysis as IV TXA administration.

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