Immunotherapy and Liver Transplantation The Future or the Failure?

center dot The increasing demand for liver transplantation (LT) for hepatocellular carcinoma (HCC) has led to the continued efforts to expand LT indications.center dot Immunotherapy has revolutionized the treatment of advanced HCC over the past few years.center dot HCC and other solid tumors exploit evolutionary conserved inhibitory immune checkpoints to evade antitumor immune response by upregulating cognate ligands or receptors capable of inhibiting antitumor immunity.