Trogocytosis drives red blood cell antigen loss in association with antibody-mediated immune suppression.

Yoelys Cruz-Leal, Peter A.A. Norris,Lazaro Gil Gonzalez,Danielle Marjoram,Hanna Wabnitz,Yuexin Shan,Alan H. Lazarus

Blood（2023）

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摘要

•Antibody-mediated immune suppression (AMIS)-inducing antibodies trigger in vivo RBC antigen and membrane loss independent of clearance•AMIS-inducing antibodies including anti-D trigger in vitro RBC antigen-loss and membrane transfer to macrophages through trogocytosis

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关键词

immune suppression,blood,antibody-mediated

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