Elderly-onset severe parkinsonism in Wilson disease: A case report.

Wilson Disease (WD) is a genetic disorder of copper metabolism with neurological and hepatic presentations caused by mutations in the ATP7B gene [ [1] Członkowska A. Litwin T. Dusek P. et al. Wilson disease. Nat. Rev. Dis. Prim. 2018; 4: 21 Crossref PubMed Scopus (418) Google Scholar ]. During the early stages, various clinical symptoms make WD challenging to diagnose and treat [ [2] Ferenci P. Członkowska A. Merle U. et al. Late-onset Wilson's disease. Gastroenterology. 2007; 132: 1294-1298 Abstract Full Text Full Text PDF PubMed Scopus (202) Google Scholar ]. It is common for WD patients to develop parkinsonism symptoms, but it rarely occurs over 351. Here, we reported an unusual case of an elderly WD patient with progressive parkinsonism and a unique therapy regimen.