Allogeneic hematopoietic stem cell transplantation for juvenile myelomonocytic leukemia with intestinal Beh?et's disease: A case report

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES(2024)

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摘要
Behcet's disease (BD) is a rare condition that is seldom associated with hematological malignancies. In this case report, we present the unique case of a 7-year-old girl diagnosed with juvenile myelomonocytic leukemia (JMML) and intestinal BD. The patient received allogeneic hematopoietic stem cell transplantation (allo-HSCT), which resulted in complete remission of both JMML and BD. Our findings suggest that allo-HSCT may be a feasible treatment option for JMML patients with coexisting BD, and holds promise for achieving remission of both illnesses. However, further clinical investigations are needed to validate these findings.
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关键词
allogeneic hematopoietic stem cell transplantation,autoimmunity,Behcet's disease,juvenile myelomonocytic leukemia,myeloid malignancy
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