The potential of ctDNA in locoregional therapies for colorectal cancer

We read with great interest the comprehensive Review by Matthew Loft and colleagues, 1 Loft M To YH Gibbs P Tie J Clinical application of circulating tumour DNA in colorectal cancer. Lancet Gastroenterol Hepatol. 2023; 8: 837-852 Summary Full Text Full Text PDF PubMed Google Scholar which highlighted the remarkable potential of circulating tumour DNA (ctDNA) in reshaping personalised management for patients with colorectal cancer, spanning various disease stages and concomitant to systemic and surgical treatments.