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LC–MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody

Yanjun Liu, Zac VanAernum, Yue Zhang,Xinliu Gao, Mariana Vlad, Bo Feng, Robert Cross,Bruce Kilgore, Alice Newman,Dongdong Wang,Hillary A. Schuessler,Douglas D. Richardson,Jennifer S. Chadwick

PHARMACEUTICAL RESEARCH（2023）

Cited 0|Views16
Key words
complementarity determining region (CDR),critical quality attribute (CQA),isomerization,LC–MS,monoclonal antibody (mab)
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