Pan-PI3K Inhibition with Copanlisib Overcomes Treg- and M 2-Tam-mediated Immune Suppression and Promotes Anti-Tumor Immune Responses

Simon Heller,Sarah Glaeske, Katja Gluske,Juliane Paul, Annika Böhme,Andreas Janzer,Helge Gottfried Roider,Anna Montebaur,Barbara Nicke,Ralf Lesche,Oliver von Ahsen,Oliver Politz,Ningshu Liu,Mátyás Gorjánácz

CLINICAL AND EXPERIMENTAL MEDICINE（2023）

引用 3|浏览11

关键词

Aliqopa,Copanlisib,Immune checkpoint inhibition,Immune suppression,PI3K pathway,Tumor microenvironment,CD8+ T cells,Tumor-associated macrophages,Tregs

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