Bac-EPIC: A web interface for developing novel efflux pump inhibitor compounds targeting Escherichia coli

Shweta Singh Chauhan, Priyam Pandey, Sabrina Manickam,Ramakrishnan Parthasarathi

Medicine in Drug Discovery(2023)

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摘要
•The emergence of MDR pathogens is a primary health concern across the globe.•Efflux pumps are a major source for offering resistance to bacteria against several broad-spectrum antibiotics, which is of primary concern as no FDA-approved EPIs exist.•Bac-EPIC – an integrated web interface has been developed to predict novel efflux pump inhibitor compounds targeting Escherichia coli.•This web interface will aid the scientific community in addressing the issue of AMR.
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关键词
inhibitor,bac-epic
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