Higher Mediterranean diet score is associated with longer time between relapses in Australian females with multiple sclerosis
arXiv (Cornell University)(2023)
摘要
A higher Mediterranean diet score has been associated with lower likelihood
of multiple sclerosis. However, evidence regarding its association with disease
activity and progression is limited. Using data from the AusLong Study, we
tested longitudinal associations (over 10 years follow-up) between the
alternate Mediterranean diet score (aMED) and aMED-Red (including moderate
consumption of unprocessed red meat) and time between relapses and disability
measured by Expanded Disability Status Scale (EDSS) (n=132; 27 males, 105
females). We used covariate-adjusted survival analysis for time between
relapses, and time series mixed-effects negative binomial regression for EDSS.
After adjusting for covariates, both higher aMED (aHR=0.94, 95%CI: 0.90, 0.99,
p=0.009) and higher aMED-Red (aHR=0.93, 95%CI: 0.89, 0.97, p=0.001) were
associated with significantly longer time between relapses in females. Whether
specific dietary components of a Mediterranean diet are important in relation
to relapses merits further study.
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关键词
multiple sclerosis,higher mediterranean diet score,mediterranean diet,relapses
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