Graphdiyne chelated AuNPs for ultrasensitive electrochemical detection of tyrosine

Tyrosine (Tyr) is a kind of amino acid that can regulate emotions and stimulate the nervous system, and it is of great importance to realize its ultrasensitive detection. A unique material of graphdiyne chelated AuNPs (GDY@AuNPs) is designed and developed to realize high-performance electrochemical sensing of Tyr. GDY promotes the absorption of Tyr via pi-pi interaction, and its C0000000000000000000000000000000000000000000000000000111111111111111000000000000000000011111111111111100000000000000000001111111111111110000000000000000000000000000000000000000000000000000C strongly chelates with AuNPs for greatly improved sensitivity. GDY@AuNPs delivers a sensitivity of up to 181.2 mu A mM-1 cm-2 and a wide range of 0.1-600 mu M, among the best for carbon or AuNPs-based materials for the detection of Tyr. It demonstrates the accurate detection of Tyr in human sweat for potential practical applications. A unique material of GDY@AuNPs is developed for electrochemical tyrosine (Tyr) sensor. Its excellent sensing performance is mainly due to the alkyne of GDY strongly chelate with AuNPs and promote the absorption of Tyr via pi-pi interaction.