Analysis of the gut microbiota in children with gastroesophageal reflux disease using metagenomics and metabolomics.

Frontiers in Cellular and Infection Microbiology(2023)

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摘要
This study provides new evidence of the pathogenesis of GERD. There are significant differences in the gut microbiota, metabolites and metabolic pathways between HCs and children with GERD, and the differences in metabolites are related to specific changes in bacterial abundance. In the future, GERD may be treated by targeting specific bacteria related to AA metabolism.
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pediatrics, gastroesophageal reflux disease, gut microbiota, metagenomics, metabolomics
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