Non-target screening and identification of the significant quality markers in the wild and cultivated Cordyceps sinensis using OPLS-DA and feature-based molecular networking

•Significant markers in cordyceps sinensis were unambiguously mined non-target screening analysis.••17 of 29 significant markers were identified by the non-target screening of FBMN, including eight wild markers and nine cultivated markers.•19 unknown samples were correctly discriminated their classification (95.5% accuracy).