Systematic review: Glycomics as diagnostic markers for hepatocellular carcinoma.

Emma Butaye,Nicky Somers, Lorenz Grossar,Nele Pauwels,Sander Lefere,Lindsey Devisscher,Sarah Raevens,Anja Geerts,Leander Meuris,Nico Callewaert,Hans Van Vlierberghe,Xavier Verhelst

Alimentary pharmacology & therapeutics（2023）

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摘要

Alterations in serum N-glycomics, characterised by increased levels of fucosylation and branching, have potential as diagnostic biomarkers for HCC. Optimisation of study design, patient selection and analysing techniques are needed before clinical implementation will be possible.

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关键词

alcohol-related liver disease, cancer-diagnosis, cirrhosis, diagnostic tests, hepatocellular carcinoma, non-alcoholic fatty liver disease, viral hepatitis

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