Case of Carbapenem-Resistant Salmonella Typhi Infection, Pakistan, 2022

Summiya Nizamuddin, Ejaz Ahmed Khan,Marie Anne Chattaway,Gauri Godbole

EMERGING INFECTIOUS DISEASES（2023）

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摘要

Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous meropenem and colistin was successful. Carbapenem-resistant Salmonella Typhi emergence will hinder treatment.

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