Immune-featured decidual stromal cells: pregnancy's multitasking superstars.

Pregnancy poses an immunological challenge, since the mother's immune system must adapt to tolerate the developing embryo until birth. The mechanisms governing this maternal-fetal dialogue have traditionally centered on the immune system. Yang et al. propose a new concept: immune-featured decidual stromal cells (DSCs), which emerge as pivotal players in mammalian maternal-fetal crosstalk.